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Brivudine

Supplier:
Catalogue number:
b6935-100 mg
Size:
100 mg
Product is available in:
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£1271.00 Estimated delivery Tue 28 Sep
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Nucleoside (thymidine) analog; DNA chain terminator, HSV-1 thymidine kinase inhibitor, HSP27 modulator.

Product Type:

Biochemicals

CAS Number:

69304-47-8

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

333.13

Reference:

Heinrich JC, Tuukkanen A, Schroeder M, et al. RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients. J Cancer Res Clin Oncol. 2011 Sep;137(9):1349-61. PMID: 21833720. Breuer M, De Loof A, Balzarini J, et al. Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Pest Manag Sci. 2005 Aug;61(8):737-41. PMID: 15838935. Spadari S, Ciarrocchi G, Focher F, et al. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol. 1995 Jun;47(6):1231-8. PMID: 7603465. Balzarini J, Bohman C, De Clercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem. 1993 Mar 25;268(9):6332-7. PMID: 8384209.

Structure:

C11H13BrN2O5

Formula:

C11H13BrN2O5

UNSPSC Code:

12352200

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