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Sarafotoxin 6c

Supplier:
Catalogue number:
s0171-2.5 mg
Size:
2.5 mg
Product is available in:
  • UK
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£1112.00 Estimated delivery Tue 28 Sep
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Isoform of a toxin found in Atractaspis engaddensis; ET-B agonist, ATP-sensitive K+ channel activator.

Product Type:

Proteins and peptides

CAS Number:

121695-87-2

Alternative Names:

SRTX-c, Sarfotoxin S6c

Storage Temp:

-20°C

Compound Purity:

≥95%

Molecular Weight:

2515.8

Reference:

Li J, Cao YX, Liu Y, et al. Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery. Microvasc Res. 2012 Mar;83(2):178-84. PMID: 22198335. Föller M, Mahmud H, Qadri SM, et al. Endothelin B receptor stimulation inhibits suicidal erythrocyte death. FASEB J. 2010 Sep;24(9):3351-9. PMID: 20427706. Tykocki NR, Gariepy CE, Watts SW. Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther. 2009 Jun;329(3):875-81. PMID: 19297422. Li M, Dai X, Watts S, et al. Increased superoxide levels in ganglia and sympathoexcitation are involved in sarafotoxin 6c-induced hypertension. Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1546-54. PMID: 18768769. Das B, Sarkar C, Shankar PR. Pretreatment with sarafotoxin 6c prior to coronary occlusion protects against infarction and arrhythmias via cardiomyocyte mitochondrial K(ATP) channel activation in the intact rabbit heart during ischemia/reperfusion. Cardiovasc Drugs Ther. 2007 Aug;21(4):243-51. PMID: 17520332.

Structure:

C103H147N27O37S5

Formula:

C103H147N27O37S5

UNSPSC Code:

12352202

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