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Saikosaponin D

Supplier:
Catalogue number:
s0134-5 mg
Size:
5 mg
Product is available in:
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£672.00 Estimated delivery Tue 28 Sep
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Triterpene saponin found in Bupleurum.

Product Type:

Biochemicals

CAS Number:

20874-52-6

Alternative Names:

Saikosaponin

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

780.98

Reference:

Zhang BZ, Guo XT, Chen JW, et al. Saikosaponin-D Attenuates Heat Stress-Induced Oxidative Damage in LLC-PK1 Cells by Increasing the Expression of Anti-Oxidant Enzymes and HSP72. Am J Chin Med. 2014 Aug 29:1-17. [Epub ahead of print] PMID: 25169909. Ying ZL, Li XJ, Dang H, et al. Saikosaponin-d affects the differentiation, maturation and function of monocyte-derived dendritic cells. Exp Ther Med. 2014 May;7(5):1354-1358. PMID: 24940438. Wong VK, Li T, Law BY, et al. Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells. Cell Death Dis. 2013 Jul 11;4:e720. PMID: 23846222. Lu XL, He SX, Ren MD, et al. Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. Mol Med Rep. 2012 Mar;5(3):637-44. PMID: 22159471. Zheng JX, Lu KQ, Xia DG, et al. Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis. Zhonghua Yi Xue Za Zhi. 2010 Mar 30;90(12):808-12. PMID: 20450618. Wang BF, Cheng YA, Dang SS. Angiogenesis inhibitory effect of saikosaponin-d on chicken embryo. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 May;29(5):425-9. PMID: 19673334. Chiang LC, Ng LT, Liu LT, et al. Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med. 2003 Aug;69(8):705-9. PMID: 14531019.

Structure:

C42H68O13

Formula:

C42H68O13

UNSPSC Code:

12352200

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