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(+)-Bicuculline

Supplier:
Catalogue number:
b3211-500 mg
Size:
500 mg
Product is available in:
  • UK
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£485.00 Estimated delivery Tue 28 Sep
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NMDA potentiator, GABA-A antagonist.

Product Type:

Biochemicals

CAS Number:

485-49-4

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

367.35

Reference:

Dela Peña IJ, Lee HL, Yoon SY, et al. The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABA(A) receptor in human neuroblastoma cells and exhibited anxiolytic-like effects in mice. Drug Discov Ther. 2013 Feb;7(1):18-23. PMID: 23524939. Torkaman-Boutorabi A, Soltani S, Oryan S, et al. Involvement of the dorsal hippocampal GABA-A receptors in histamine-induced facilitation of memory in the Morris water maze. Pharmacol Biochem Behav. 2013 Apr;105:142-50. PMID: 23438692. Ionov ID, Roslavtseva LA. Coadministration of bicuculline and NMDA induces paraplegia in the rat. Brain Res. 2012 Apr 27;1451:27-33. PMID: 22445063 Ji G, Neugebauer V. Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors. J Neurophysiol. 2011 Nov;106(5):2642-52. PMID: 21880942. Costa LG, Doctor SV, Murphy SD. Antinociceptive and hypothermic effects of trimethyltin. Life Sci. 1982 Sep 13;31(11):1093-102. PMID: 6890611. Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Res. 1982 Jan 28;232(1):41-56. PMID: 7055710.

Structure:

C20H17NO6

Formula:

C20H17NO6

UNSPSC Code:

12352200

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