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Glabridin

Supplier:
Catalogue number:
g4400-25 mg
Size:
25 mg
Product is available in:
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£423.00 Estimated delivery Tue 28 Sep
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Isoflavonoid found in Glycyrrhiza; GABA-A positive modulator.

Product Type:

Biochemicals

CAS Number:

59870-68-7

Alternative Names:

(R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

324.37

Reference:

Jin Z, Kim S, Cho S, et al. Potentiating Effect of Glabridin on GABAA Receptor-Mediated Responses in Dorsal Raphe Neurons. Planta Med. 2013 Aug 23. [Epub ahead of print]. PMID: 23975867. Kim HS, Suh KS, Ko A, et al. The flavonoid glabridin attenuates 2-deoxy-D-ribose-induced oxidative damage and cellular dysfunction in MC3T3-E1 osteoblastic cells. Int J Mol Med. 2013 Jan;31(1):243-51. PMID: 23128413. Ahn J, Lee H, Jang J, et al. Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice. Food Chem Toxicol. 2013 Jan;51:439-45. PMID: 22967722. Lee JW, Choe SS, Jang H, et al. AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity. J Lipid Res. 2012 Jul;53(7):1277-86. PMID: 22493094. Hasanein P. Glabridin as a major active isoflavan from Glycyrrhiza glabra (licorice) reverses learning and memory deficits in diabetic rats. Acta Physiol Hung. 2011 Jun;98(2):221-30. PMID: 21616781. Tsai YM, Yang CJ, Hsu YL, et al. Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway. Integr Cancer Ther. 2011 Dec;10(4):341-9. PMID: 21059620.

Structure:

C20H20O4

Formula:

C20H20O4

UNSPSC Code:

12352200

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