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Bosutinib, structural isomer

Supplier:
Catalogue number:
b5875-100 mg
Size:
100 mg
Product is available in:
  • UK
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£803.00 Estimated delivery Tue 5 Oct
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Bosutinib isomer; Src and Abl inhibitor.

Product Type:

Biochemicals

CAS Number:

1391063-17-4

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

530.45

Reference:

Rassi FE, Khoury HJ. Bosutinib: a SRC-ABL tyrosine kinase inhibitor for treatment of chronic myeloid leukemia. Pharmgenomics Pers Med. 2013 Aug 5;6:57-62. PMID: 24019749. Lonskaya I, Hebron ML, Desforges NM, et al. Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance. EMBO Mol Med. 2013 Aug;5(8):1247-62. PMID: 23737459. Ulmer A, Tabea Tauer J, Glauche I, et al. TK inhibitor treatment disrupts growth hormone axis: clinical observations in children with CML and experimental data from a juvenile animal model. Klin Padiatr. 2013 May;225(3):120-6. PMID: 23716272. Amsberg GK, Schafhausen P. Bosutinib in the management of chronic myelogenous leukemia. Biologics. 2013;7:115-22. PMID: 23674887. Kim WG, Guigon CJ, Fozzatti L, et al. SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer. Clin Cancer Res. 2012 Mar 1;18(5):1281-90. PMID: 22271876.

Structure:

C26H29Cl2N5O3

Formula:

C26H29Cl2N5O3

UNSPSC Code:

12352200

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