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20(S)-Ginsenoside Rh2

Supplier:
Catalogue number:
g3453-10 mg
Size:
10 mg
Product is available in:
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£479.00 Estimated delivery Tue 28 Sep
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Triterpene saponin found in Panax.

Product Type:

Biochemicals

CAS Number:

78214-33-2

Alternative Names:

20S-GinsenosideRh2, 20S-protopanaxdiol-3-O-β-D- glucopyranoside, β-D-Glucopyranoside

Storage Temp:

4°C

Compound Purity:

≥98%

Molecular Weight:

640.89

Reference:

Fatmawati S, Ersam T, Yu H, et al. 20(S)-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng. Bioorg Med Chem Lett. 2014 Aug 12. [Epub ahead of print]. PMID: 25152999. Shi Q, Li J, Feng Z, et al. Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: Recruiting histone deacetylase and inhibiting activator protein 1 transcription factors. Mol Med Rep. 2014 Jul 18. [Epub ahead of print]. PMID: 25051397. Li S, Gao Y, Ma W, et al. EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2. Tumour Biol. 2014 Jun;35(6):5593-8. PMID: 24557544. Qiu J, Li W, Feng SH, et al. Ginsenoside Rh2 promotes nonamyloidgenic cleavage of amyloid precursor protein via a cholesterol-dependent pathway. Genet Mol Res. 2014 May 9;13(2):3586-98. PMID: 24854439. Yi PF, Bi WY, Shen HQ, et al. Inhibitory effects of sulfated 20(S)-ginsenoside Rh2 on the release of pro-inflammatory mediators in LPS-induced RAW 264.7 cells. Eur J Pharmacol. 2013 Jul 15;712(1-3):60-6. PMID: 23665488. Choi WY, Lim HW, Lim CJ. Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2 in cultured macrophages and keratinocytes. J Pharm Pharmacol. 2013 Feb;65(2):310-6. PMID: 23278699. He L, Lee J, Jang JH, et al. Ginsenoside Rh2 inhibits osteoclastogenesis through down-regulation of NF-κB, NFATc1 and c-Fos. Bone. 2012 Jun;50(6):1207-13. PMID: 22484180. Wang Y, Wang H, Liu Y, et al. Antihyperglycemic effect of ginsenoside Rh2 by inducing islet β-cell regeneration in mice. Horm Metab Res. 2012 Jan;44(1):33-40. PMID: 22205570.

Structure:

C36H62O8 H2O

Formula:

C36H62O8 H2O

UNSPSC Code:

12352200

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