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Risedronate Sodium Hydrate

Supplier:
Catalogue number:
r3373-100 mg
Size:
100 mg
Product is available in:
  • UK
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£177.00 Estimated delivery Tue 28 Sep
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Bisphosphonate; inhibits transfer of farnesyl pyrophosphate.

Product Type:

Biochemicals

CAS Number:

329003-65-8

Alternative Names:

Risedronic acid monosodium salt, Actonel, Optinate

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

350.13

Reference:

Lems WF, den Heijer M. Established and forthcoming drugs for the treatment of osteoporosis. Neth J Med. 2013 May;71(4):188-93. PMID: 23723112. Jin J, Wang L, Wang XK, et al. Risedronate inhibits bone marrow mesenchymal stem cell adipogenesis and switches RANKL/OPG ratio to impair osteoclast differentiation. J Surg Res. 2013 Mar;180(1):e21-9. PMID: 22487394. Matsumoto T, Nagase Y, Iwasawa M, et al. Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis. Arthritis Rheum. 2011 Dec;63(12):3908-17. PMID: 21898348. Jordão FM, Saito AY, Miguel DC, et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31. PMID: 21357292.

Structure:

C7H10NO7P2Na 2.5H2O

Formula:

C7H10NO7P2Na 2.5H2O

UNSPSC Code:

12352200

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