Cl-Amidine (hydrochloride)
Catalogue number:
CAY10599-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
£191.00
Estimated delivery Wed 1 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1373232-26-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
347.2
Alternative Names:
n-[(1s)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PAD inhibitor (IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively); cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 µM, respectively); reduces ex vivo extracellular NET formation and increases survival in a mouse model of CLP-induced sepsis at 50 mg/kg; decreases the citrulline content in serum and joints and reduces the development of IgG autoantibodies in a mouse model of collagen-induced arthritis
Storage Temperature:
-20°C