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BRD2 bromodomain 1 TR-FRET Assay Kit

Catalogue number:
CAY600500-9600 wells
Supplier:
Size:
9600 wells _$$_
Product is available in:
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Alternative Names:

bromodomain containing protein 2, ring3, rnf3

Product Description:

Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of BRD2 and BRD4 bind acetylated histone tails, which couples histone acetylation marks to the transcriptional regulation of target promoters. Small molecule inhibitors of bromodomain interactions hold promise as useful therapeutics for human disease. Cayman’s BRD2 Bromodomain 1 TR-FRET Assay Kit is a homogeneous, TR-FRET assay method amenable to rapid characterization of inhibitors of bromodomain/acetylated peptide interaction in a high throughput format. This screening assay kit is robust, displaying a Z' >0.6.

Storage Temperature:

-80°C

CAY600500-9600 wells: BRD2 bromodomain 1
CAY600500-9600 wells: BRD2 bromodomain 1 TR-FRET Assay Kit
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