Purity:
≥70% estimated by SDS-PAGE
Alternative Names:
jumonji domain containing 2d, kdm4d, lysine-specific demethylase 4d
- Data sheet: View or download
- MSDS: View or download
Product Description:
Source: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli • Mr: 42.6 kDa • JMJD2D catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me2/3), leading to transcriptional repression and activation, respectively. JMJD2D is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity. Therefore this protein is purified by Strep-Tactin affinity chromatography.
Storage Temperature:
-80°C