Purity:
≥95% estimated by SDS-PAGE
Alternative Names:
jhdm3a, jumonji domain containing 2a, kdm4a, lysine (k)-specific demethylase 4a
Product Description:
Source: Recombinant N-terminal Strep II-tagged protein expressed in E. coli • Mr: 42.7 kDa • JMJD2A catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. JMJD2A is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can result in displacement of the catalytic iron and decreased activity. Therefore this protein is purified by Strep-Tactin affinity chromatography.
Storage Temperature:
-80°C