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Hamster Anti-Mouse TCRγδ-AF488

Catalogue number:
Supplier:
Size:
0.1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£243.00 Estimated delivery Fri 26 Aug
Shipping is calculated in checkout
Applications:

FC

Antibody Host:

Hamster

Species Reactivity:

Mouse

Antibody Isotype:

IgG

Antibody Type:

Monoclonal

Immunogen:

Mouse T cell clone G8

BALB/c mouse thymocytes were stained wit

The TCRγδ heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of γδ TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are γδ+ and have limited receptor diversity. The TCRγδ heterodimer recognises peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the γδ heterodimer and plate-bound UC7-13D5 activates γδ TCR-bearing cells. This antibody does not react with αβ TCR-expressing T cells.

Storage Temperature:

2 - 8°C

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