CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
Mac-1α, Mo-1, CR3, integrin αM, C3biR, ITGAM, CR3A, p170
Human, Porcine, Rhesus, Cynomolgus, Chimpanzee, Baboon
Rheumatoid synovial cells and human monocytes
2 - 8°C