Rat Anti-Mouse CD107a-AF488
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FC, IHC-FS, IHC-PS, ICC, WB
Rat
Mouse
IgG2a
Monoclonal
Plasma membrane fraction of mouse embryo NIH/3T3 cell line
LAMP-1, lysosomal-associated membrane protein 1
- Data sheet: View or download
- MSDS: View or download
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.
2 - 8°C