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Rat Anti-Mouse CD107a-AF488

Catalogue number:
Supplier:
Size:
0.1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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£243.00 Estimated delivery Fri 26 Aug
Shipping is calculated in checkout
Applications:

FC, IHC-FS, IHC-PS, ICC, WB

Antibody Host:

Rat

Species Reactivity:

Mouse

Antibody Isotype:

IgG2a

Antibody Type:

Monoclonal

Immunogen:

Plasma membrane fraction of mouse embryo NIH/3T3 cell line

Alternative Names:

LAMP-1, lysosomal-associated membrane protein 1

Mouse Mφ cells were intracellularly stai

CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.

Storage Temperature:

2 - 8°C

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