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CAS Number:
1012054-59-9
Purity:
≥98% by HPLC
Molecular Weight:
434
Alternative Names:
7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC₅₀ values of 4.4, 2.4, and 15.7 nM, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
Storage Temperature:
-20°C
