BAY-850
Catalogue number:
CAY23422-1 mg
Supplier:
Size:
1 mg
Product is available in:
£62.00
Estimated delivery Wed 17 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2099142-76-2
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C38H44ClN5O3
Molecular Weight:
654.2
Alternative Names:
n-[(1r)-2-
- MSDS: View or download
Product Description:
An ATAD2 inhibitor (IC50 = 22 nM in a TR-FRET assay using a tetra-acetylated histone H4 peptide); selective for ATAD2 over a panel of 32 bromodomain family proteins, including ATAD2B, a panel of 354 kinases, and a panel of 25 GPCRs at 1 µM; induces apoptosis and cell cycle arrest in, and inhibits proliferation, invasion, and migration of, PA-1 and SKOV3 ovarian cancer cells at 5 µM; reduces tumor volume and the percentage of lung metastases in a SKOV3 mouse xenograft model at 20 mg/kg