SIRT2 Inhibitor, AGK2
Catalogue number:
1651-10
Supplier:
BioVision
Size:
10 mg _$$_
Product is available in:
N/A
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CAS Number:
304896-28-4
Purity:
≥95% by HPLC
Molecular Weight:
434
Alternative Names:
AGK2, (2E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of sirtuin 2 (SIRT2) (IC₅₀ = 3.5 µM). AGK2 is >15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued α-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson’s disease.
Storage Temperature:
4°C
