CTPI-2
Catalogue number:
HY-123986-250mg
Supplier:
Size:
250 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
68003-38-3
Purity:
99.95
Molecular Formula:
C13H9ClN2O6S
Molecular Weight:
356.74
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 µM. CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity[1][2].