PB 28 (hydrochloride)
Catalogue number:
CAY31742-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£181.00
Estimated delivery Wed 1 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
172907-03-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
443.5
Alternative Names:
1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]-piperazine, dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A σ receptor ligand with anticancer and antiviral activites; binds to σ1 and σ2 receptors (Kis = 13 and 0.28 nM, respectively, in MCF-7 cell membranes); selective for σ1 and σ2 receptors over hERG channels (Ki = 1,000 nM); inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s = 25 and 15 nM, respectively); decreases basal P-gp levels in the same cells; reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 = 278 nM)
Storage Temperature:
-20°C