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Human CellExp™ MMP-13, Human Recombinant

Supplier:
Catalogue number:
P1566-10
Size:
10 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£352.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

MMP13 or collagenase 3 is an endopeptidase that is part of the calcium and zinc dependent matrix metalloproteinase family. Like most MMPs, it is secreted as an inactive pro-form and is activated once its pro-domain is cleaved. Additionally, MMP13 is expressed by fibroblasts, chondrocytes, and squamous epithelial cells. MMP-13 (Collagenase-3) has been demonstrated to degrade a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X and XIV, gelatin, aggrecan, perlecan and fibronectin. Furthermore, it is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

Product Type:

Proteins and peptides

Alternative Names:

Collagenase 3, Matrix metalloproteinase-13, CLG 3, CLG3EC, EC 3.4.24.22

Storage Temp:

-20°C

Molecular Weight:

536-

UNSPSC Code:

12352202

Human CellExp™ MMP-13, Human Recombinant

Human CellExp™ MMP-13, Human Recombinant

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