www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Human CellExp™ GDF-15, Human Recombinant

Supplier:
Catalogue number:
P1546-10
Size:
10 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£224.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Growth Differentiation Factor 15 (GDF15), also known as Macrophage inhibitory cytokine 1 (MIC-1), is a protein belonging to the TGF-beta superfamily. Like other proteins in the superfamily, it is expressed as a large precursor protein and cleaved at an (RxxR) furin-like cleavage site to release the mature protein. GDF15 is highly expressed in mammalian tissue with higher levels in the placenta and brain and lower levels in the kidney, prostate, colon. Its expression is tightly regulated and often induced in response to cellular stress. Additionally, GDF15 has been shown to have various functions, including inhibition of Tumor Necrosis Factor alpha (TNF-alpha) production from lipopolysaccharide-stimulated macrophages and the induction of cartilage formation. Some studies have also implicated GDF15 serum levels to have a strong association with many diseases like cancer, cardiovascular diseases, and obesity, and could potentially serve as a reliable biomarker for disease progression.

Product Type:

Proteins and peptides

Alternative Names:

Growth Differentiation Factor 15, MIC-1, Macrophage Inhibitory Cytokine 1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor

Storage Temp:

-20°C

Molecular Weight:

12--

UNSPSC Code:

12352202

Human CellExp™ GDF-15, Human Recombinant

Human CellExp™ GDF-15, Human Recombinant

Details Cat number & supplier Size Price
Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) P1527-50 · BioVision
P1527-50
BioVision
50 µg £888.00
50 µg
view
Human CellExp™ GDF-15, Human Recombinant P1546-50 · BioVision
P1546-50
BioVision
50 µg £888.00
50 µg
view
Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) P1527-10 · BioVision
P1527-10
BioVision
10 µg £224.00
10 µg
view
Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2), Recombinant P1547-10 · BioVision
P1547-10
BioVision
10 µg £186.00
10 µg
view
Human CellExp™ Coronavirus Spike Protein (SARS-CoV-2), Recombinant P1547-50 · BioVision
P1547-50
BioVision
50 µg £760.00
50 µg
view
Recombinant Hepatitis C Virus Core Protein P1548-100 · BioVision
P1548-100
BioVision
100 µg £249.00
100 µg
view
Recombinant Hepatitis C Virus Core Protein P1548-500 · BioVision
P1548-500
BioVision
500 µg £1015.00
500 µg
view