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R-7050

Supplier:
Catalogue number:
B3063-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£307.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

R-7050 is a cell-permeable inhibitor of signaling through the TNFα receptor (TNFαR) complex. It blocks the formation of signal-initiating complexes that consist of TNFα receptor (TNFαR) I, TNFαR associated death domain protein (TRADD) and receptor interacting protein 1 (RIP1) through inhibition of ligand-induced receptor endocytosis. It inhibits TNFα-induced intercellular adhesion molecule 1 (ICAM-1) expression with an EC₅₀ of 0.631 µM. It (6-12 mg/kg) improves neurovascular injury after intracerebral hemorrhage in mice.

Product Type:

Biochemicals

CAS Number:

303997-35-5

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

380.77

UNSPSC Code:

12352200

R-7050

R-7050

Details Cat number & supplier Size Price
R-7050 B3063-1 · BioVision
B3063-1
BioVision
1 mg £77.00
1 mg
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25 mg
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C87 B3062-5 · BioVision
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5 mg
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JTE-607 B3064-5 · BioVision
B3064-5
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5 mg £160.00
5 mg
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C87 B3062-25 · BioVision
B3062-25
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25 mg £818.00
25 mg
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BAY-678 B3061-5 · BioVision
B3061-5
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5 mg £224.00
5 mg
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BAY-678 B3061-25 · BioVision
B3061-25
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25 mg £888.00
25 mg
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