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CAS Number:
332420-90-3
Purity:
≥98%
Molecular Weight:
502
Alternative Names:
4-[(4-chloro-3-nitrophenyl)diazenyl]-5-phenyl-2-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-3-one; 3-phenyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazole-4,5-dione 4-({4-chloro-3-nitrophenyl}hydrazone); 4-[(E)-2-(4-chloro-3-nitrophenyl)hydrazono]-5-phenyl-2-(4-phe
- Data sheet: View or download
- MSDS: View or download
Product Description:
C87 is an inhibitor of Tumor Necrosis Factor α (TNFα). It binds to human TNFα with a KD of 110 nM and potently inhibits TNFα-induced cytotoxicity in L929 cells with an IC₅₀ of 8.73 µM. It effectively blocks TNFα-triggered signaling pathways and attenuates TNFα-induced inflammation in a mouse model of hepatitis.
Storage Temperature:
-20°C