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C87

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

332420-90-3

Purity:

≥98%

Molecular Weight:

502

Alternative Names:

4-[(4-chloro-3-nitrophenyl)diazenyl]-5-phenyl-2-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-3-one; 3-phenyl-1-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazole-4,5-dione 4-({4-chloro-3-nitrophenyl}hydrazone); 4-[(E)-2-(4-chloro-3-nitrophenyl)hydrazono]-5-phenyl-2-(4-phe

Product Description:

C87 is an inhibitor of Tumor Necrosis Factor α (TNFα). It binds to human TNFα with a KD of 110 nM and potently inhibits TNFα-induced cytotoxicity in L929 cells with an IC₅₀ of 8.73 µM. It effectively blocks TNFα-triggered signaling pathways and attenuates TNFα-induced inflammation in a mouse model of hepatitis.

Storage Temperature:

-20°C

C87
C87