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Tucidinostat

Supplier:
Catalogue number:
B3059-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£115.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

Tucidinostat is an inhibitor of histone deacetylases (HDACs) with IC₅₀ values of 95 nM, 160 nM, 67 nM and 78 nM for HDAC1, HDAC2, HDAC3 and HDAC10 respectively. It shows potent antitumor activity. It inhibits several human derived tumor cell lines, such as HL-60, U2OS, LNCaP with GI₅₀ values of 0.4-40 µM but has no effect on the growth of non-cancerous CCC-HEK human fetal kidney or CCC-HEL human liver cells. It (12.5-50 mg/kg, p.o) reduces tumor growth in mouse xenograft models.

Product Type:

Biochemicals

CAS Number:

1616493-44-7

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

390.41

UNSPSC Code:

12352200

Tucidinostat

Tucidinostat

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