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CAS Number:
19216-56-9
Purity:
≥95%
Molecular Weight:
383
Alternative Names:
Furazosin; [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanon
- Data sheet: View or download
- MSDS: View or download
Product Description:
Prazosin is an antagonist of α1-adrenergic receptors (α1-ARs). The affinity estimates (pKi) for inhibition of [3H]-prazosin binding to CHO-K1 cells expressing cloned human α1A, α1B and α1D adrenoceptors are 9.0, 9.9 and 9.5 respectively. It also inhibits α2-ARs with Ki values of 340 nM and 3.7 nM in α2A-AR expressing HT-29 cells and α2B-AR expressing NG108 cells respectively. It is used in the treatment of hypertension, anxiety and post-traumatic stress disorder. It is in clinical trials to prevent cytokine storm in patients with COVID-19.
Storage Temperature:
-20°C
