www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

RIPA-56

Supplier:
Catalogue number:
B3051-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£83.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of Receptor-Interacting Protein 1 (RIP1) kinase with an IC₅₀ of 13 nM. It protects HT-29 cells against TNFα-induced necroptosis with an EC₅₀ of 28 nM. RIPA-56 efficiently reduces TNFα-induced mortality and multiorgan damage in a systemic inflammatory response syndrome (SIRS) mice model. Modulators of RIP kinase 1 may be beneficial against SARS-CoV-2 based on interaction of RIP kinase 1 with SARS-CoV-2 protein Nsp12.

Product Type:

Biochemicals

CAS Number:

1956370-21-0

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

221.29

UNSPSC Code:

12352200

RIPA-56

RIPA-56

Details Cat number & supplier Size Price
RIPA-56 B3051-25 · BioVision
B3051-25
BioVision
25 mg £332.00
25 mg
view
Omeprazole B3052-1000 · BioVision
B3052-1000
BioVision
1 g £135.00
1 g
view
Astemizole B3050-5 · BioVision
B3050-5
BioVision
5 mg £77.00
5 mg
view
Omeprazole B3052-500 · BioVision
B3052-500
BioVision
500 mg £77.00
500 mg
view
Astemizole B3050-25 · BioVision
B3050-25
BioVision
25 mg £307.00
25 mg
view
Siramesine B3053-1 · BioVision
B3053-1
BioVision
1 mg £109.00
1 mg
view
PRE-084 Hydrochloride B3049-5 · BioVision
B3049-5
BioVision
5 mg £77.00
5 mg
view