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CAS Number:
68844-77-9
Purity:
≥98%
Molecular Weight:
458
Alternative Names:
Hismanal; Histaminos; Paralergin; NSC 329963; 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine; 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole; R 43512
- Data sheet: View or download
- MSDS: View or download
Product Description:
Astemizole is a histamine H1-receptor antagonist, with an IC₅₀ of 4 nM. Astemizole also shows potent hERG potassium channel blocking activity with an IC₅₀ of 0.9 nM. Astemizole shows synergistic antiproliferative effects with calcitriol in breast cancer cells and in vivo preclinical models by blocking the EAG1 potassium channel. High throughput screens have shown that astemizole is a promising candidate for stopping replication of SARS-CoV-2 virus.
Storage Temperature:
-20°C
