SA4503 dihydrochloride
Catalogue number:
B3046-5
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
N/A
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CAS Number:
165377-44-6
Purity:
≥98%
Molecular Weight:
441
Alternative Names:
Cutamesine dihydrochloride; 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine;dihydrochloride; 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine 2HCl; AGY94806 dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
SA4503 is a potent sigma-1 (σ1 receptor) agonist. It shows 100 fold higher affinity for σ1 than σ2 receptor with IC₅₀ values of 17.4 nM and 1784 nM against 200 nM (+)-pentazocine for binding σ receptor in guinea pig brain membranes. It shows Ki values of 4.6 nM and 63.1 nM for σ1 and σ2 sites respectively in guinea pig brain homogenates. It enhances recovery of lost sensorimotor function in a rat model of stroke. Based on viral screens, modulators of sigma receptor are predicted to show activity against SARS-CoV-2.
Storage Temperature:
-20°C
