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Umifenovir

Supplier:
Catalogue number:
B3040-25
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£332.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Umifenovir is an indole derivative with broad-spectrum antiviral activity. It inhibits virus-mediated fusion with target membrane and blocks virus entry into target cells. It shows antiviral activity against many enveloped or non-enveloped RNA or DNA viruses with IC₅₀ values ranging from 0.41 to 16 uM. It (50 or 100 mg/kg/day) reduces mean pulmonary virus yields and the rate of mortality in mice infected with FLU-A (A/PR/8/34 H1N1). Molecular dynamics and structural analysis show that Umifenovir may target SARS-CoV-2 spike glycoprotein and may block its trimerisation which will reduce cell adherence and virus entry.

Product Type:

Biochemicals

CAS Number:

131707-25-0

Storage Temp:

-20°C

Compound Purity:

≥95%

Molecular Weight:

477.41

UNSPSC Code:

12352200

Umifenovir

Umifenovir

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