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Siponimod (BAF-312)

Supplier:
Catalogue number:
B3037-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£90.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Siponimod is an orally bioavailable agonist of the sphingosine-1-phosphate (S1P) receptor that is selective for S1P1 and S1P5 with EC₅₀ values of 0.39 and 0.98 nM respectively, in a GTPγS-binding assay. Siponimod (0.3 or 3 mg/kg/day mg/kg/day) reduces experimental autoimmune encephalomyelitis (EAE) symptoms in rats. It significantly attenuates demyelination in organotypic cerebellar slice cultures. It is used for the treatment of relapsing forms of multiple sclerosis.

Product Type:

Biochemicals

CAS Number:

1230487-00-9

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

516.6

UNSPSC Code:

12352200

Siponimod (BAF-312)

Siponimod (BAF-312)

Details Cat number & supplier Size Price
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