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Nidufexor

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

1773489-72-7

Purity:

≥98%

Molecular Weight:

487

Alternative Names:

LMB 763; 4-[[benzyl-(8-chloro-1-methyl-4H-chromeno[4,3-c]pyrazole-3-carbonyl)amino]methyl]benzoic acid; 4-((N-benzyl-8-chloro-1-methyl-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamido)methyl)benzoic acid; Benzoic acid, 4-((((8-chloro-1,4-dihydro-1-methyl(

Product Description:

Nidufexor is an agonist of Farnesoid X receptor (FXR). Administration of Nidufexor (10 and 30 mg/kg for 3 weeks) modulates FXR-dependent genes in vivo leading to the reduction of steatosis, inflammation, and fibrosis in a murine NASH model. It is in clinical trials in patients with nonalcoholic steatohepatitis (NASH) and diabetic nephropathy.

Storage Temperature:

-20°C

Nidufexor
Nidufexor