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Licogliflozin

Supplier:
Catalogue number:
B3028-1
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£173.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Licogliflozin is a dual inhibitor of Sodium/glucose cotransporters SGLT1 and SGLT2 with a higher selectivity for SGLT2 (in vitro IC₅₀ values of 20.6 and 0.58 nM, respectively). It causes a reduction in body weight from baseline versus placebo after 24 weeks (50 mg twice daily). However, the percent decreases were numerically small (<5%). Higher doses of licogliflozin also reduce waist circumference, fasting plasma glucose, hemoglobin A1c (HbA1c), systolic blood pressure and triglycerides. It increases HDL cholesterol and 24‐hour urinary glucose excretion.

Product Type:

Biochemicals

CAS Number:

1291094-73-9

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

416.46

UNSPSC Code:

12352200

Licogliflozin

Licogliflozin

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