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Cenicriviroc

Supplier:
Catalogue number:
B3026-5
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£409.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Cenicriviroc is a potent inhibitor of C-C chemokine receptors CCR5 and CCR2. It is an orally bioavailable derivative of TAK-779 with potent anti-HIV-1 activity. It blocks the binding of MIP-1α and MIP-1β to CCR5 with an IC₅₀ of 2.3 nM. It inhibits the binding of MCP-1 to CCR2b with an IC₅₀ of 5.9 nM. It inhibits the replication of R5X4HIV-1 in U87.CD4.CCR5 cells at a concentration of 100 nM. It shows potent anti-inflammatory and antifibrotic activity in animal models of fibrosis.

Product Type:

Biochemicals

CAS Number:

497223-25-3

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

696.94

UNSPSC Code:

12352200

Cenicriviroc

Cenicriviroc

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