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Maduramicin Ammonium

Catalogue number:
Supplier:
BioVision
Size:
5 mg _$$_
Product is available in:
  • UK
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CAS Number:

84878-61-5

Purity:

>95%

Molecular Weight:

934

Alternative Names:

azane,2-[(2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-[(2R,3S,5R)-3-[(2R,4S,5S,6S)-4,5-dimethoxy-6-methyloxan-2-yl]oxy-5-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyloxan-2-yl]oxolan-2-yl]-5-methyloxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspir

Product Description:

Maduramicin is a natural polyether ionophore antibiotic first isolated from the actinomycete Actinomadura rubra. It is commonly used in veterinary medicine as an anti-coccidial agent. It is cytotoxic against Cryptosporidium parvum infection in Swiss mice at a dosage of 1-2.5 mg/kg body weight. Maduramicin has an EC₅₀ of 14.8 nM against late-stage gametocyte viability and significantly blocks in vivo transmission in a mouse model of malaria transmission.

Storage Temperature:

-20°C

Maduramicin Ammonium
Maduramicin Ammonium