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CAS Number:
1891087-61-8
Purity:
≥98% by HPLC
Molecular Weight:
534
Alternative Names:
BAY1816032,2-(3,5-difluoro-4-((3-(5-methoxy-4-((3-methoxypyridin-4-yl)amino)pyrimidin-2-yl)-1H-indazol-1-yl)methyl)phenoxy)ethan-1-ol
- Data sheet: View or download
- MSDS: View or download
Product Description:
BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM. Displays excellent selectivity over a panel of 395 kinases. BAY 1816032 abrogates nocodazole-induced Thr-120 phosphorylation of the major BUB1 target protein histone H2A in HeLa cells with an IC50 of 29 nanomol/L, induces lagging chromosomes and mitotic delay.
Storage Temperature:
-20°C
