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CAS Number:
2243736-45-8
Purity:
≥98%
Molecular Weight:
392
Alternative Names:
FB-232,FTO inhibitor,2-((2,6-dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)-N-hydroxybenzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
FB23-2 is a potent FTO (fat mass and obesity-associated) inhibitor. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity (IC50 = 2.6 µM). Mimicking FTO depletion, FB23-2 dramatically suppresses proliferation and promotes the differentiation/apoptosis of human acute myeloid leukemia (AML) cell line cells and primary blast AML cells in vitro.
Storage Temperature:
-20°C
