Bisantrene dihydrochloride
Catalogue number:
B2736-25
Supplier:
BioVision
Size:
25 mg _$$_
Product is available in:
N/A
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CAS Number:
78186-34-2
Purity:
≥98%
Molecular Weight:
471
Alternative Names:
NSC 337766,N-[(E)-[10-[(E)-(4,5-dihydro-1H-imidazol-2-ylhydrazinylidene)methyl]anthracen-9-yl]methylideneamino]-4,5-dihydro-1H-imidazol-2-amine;dihydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
Bisantrene dihydrochloride is the hydrochloride salt of an anthracenyl bishydrazone with antineoplastic activity. It intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin (Cat. No. 1527) in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. Bisantrene can be used to select for P-glycoprotein-mediated multiple drug resistance
Storage Temperature:
-20°C
