Ketoconazole
Catalogue number:
B2735-250
Supplier:
BioVision
Size:
250 mg _$$_
Product is available in:
N/A
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CAS Number:
65277-42-1
Purity:
≥98%
Molecular Weight:
531
Alternative Names:
Fungoral,1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
- Data sheet: View or download
- MSDS: View or download
Product Description:
Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. Ketoconazole also inhibits human CYP3A4 (IC50 = 0.54 µM). Formulations containing ketoconazole have been used in the treatment of fungal infections.
Storage Temperature:
-20°C