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Adapalene

Supplier:
Catalogue number:
B2733-10
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£109.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Adapalene is a synthetic Retinoic acid analog that acts as a RARβ and RARγ agonist (AC₅₀ values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. Adapalene (10 µM) completely inhibits the activity of soybean 15-lipoxygenase (15-LOX) in an enzyme assay and inhibits the 5- and 15-LOX pathways in human blood polymorphonuclear leukocytes (PMNs).

Product Type:

Biochemicals

CAS Number:

106685-40-9

Storage Temp:

-20°C

Compound Purity:

≥98% by HPLC

Molecular Weight:

412.53

UNSPSC Code:

12352200

Adapalene

Adapalene

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