N/A
Shipping is calculated in checkout
This product is no longer available to order.
CAS Number:
1401242-74-7
Purity:
≥98%
Molecular Weight:
471
Alternative Names:
VU0458298-2,(2R)-N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide,ML277,CID-53347902
- Data sheet: View or download
- MSDS: View or download
Product Description:
ML-277 is a potent activator of KCNQ1 (Kv7.1) channels (EC₅₀ = 260nM). It displays >100-fold selectivity versus KCNQ2 and KCNQ4 and no activity against the hERG potassium channel up to 30 µM. KCNQ1 is a voltage-gated potassium channel required for repolarization phase of the cardiac action potential.
Storage Temperature:
-20°C
