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Losmapimod

Catalogue number:
Supplier:
BioVision
Size:
25 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

585543-15-3

Purity:

≥98% by HPLC

Molecular Weight:

383

Alternative Names:

,GW-856553,6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide

Product Description:

Losmapimod is a potent and selective p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, respectively. Displays no significant activity for p38γ, p38δ (<25% inhibition at 10 uM), and COX-2; significantly and dose-dependently improves survival, endothelial-dependent and -independent vascular relaxation in rat model of cardiovascular disease.

Storage Temperature:

-20°C

Losmapimod
Losmapimod