N/A
Shipping is calculated in checkout
This product is no longer available to order.
CAS Number:
585543-15-3
Purity:
≥98% by HPLC
Molecular Weight:
383
Alternative Names:
,GW-856553,6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
Losmapimod is a potent and selective p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, respectively. Displays no significant activity for p38γ, p38δ (<25% inhibition at 10 uM), and COX-2; significantly and dose-dependently improves survival, endothelial-dependent and -independent vascular relaxation in rat model of cardiovascular disease.
Storage Temperature:
-20°C