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CAS Number:
5119-48-2
Purity:
≥98%
Molecular Weight:
470
Alternative Names:
NSC 101088,5β,6β-epoxy-4β,22R,27-trihydroxy-1-oxo-δ-lactone-ergosta-2,24-dien-26-oic acid,NSC 273757
- Data sheet: View or download
- MSDS: View or download
Product Description:
Withaferin A is a steroid lactone that displays potent anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) sprouting in vitro (IC50 = 12 nM) and in vivo. Prevents NF-κB activation by inhibiting activation of IKKβ. Also inhibits chymotrypsin-like activity of the 20S proteasome.
Storage Temperature:
-20°C