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Anti-CD19 (Inebilizumab), Humanized Antibody

Supplier:
Catalogue number:
A2173-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£581.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

The research-grade biosimilar is a humanised afucosylated monoclonal antibody that is directed against CD19. CD19 is a cell surface antigen that is expressed on pre- as well as mature B lymphocytes and is required for proliferation, differentiation, activation of B cells, and antibody production. Although the precise mechanism is not known, it is presumed that the antibody binds to CD19 located on the malignant B cell surface and results in antibody-mediated cellular cytotoxicity. The original drug received approval from the FDA in 2020 to treat neuromyelitis optica spectrum disorder (NMOSD) in patients who were anti-aquaporin 4 (AQP4) positive

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-80°C

Antibody Host:

Recombinant

Antibody Isotype:

IgG1, kappa

Formulation:

In PBS, pH 7.5

Antibody Type:

Monoclonal

UNSPSC Code:

12352203

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