Anti-CTLA-4 (Tremelimumab), Human IgG2 Antibody
Catalogue number:
A2163-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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This product is no longer available to order.
Antibody Host:
Recombinant
Species Reactivity:
Human
Antibody Isotype:
IgG2, kappa
Antibody Type:
Monoclonal
Immunogen:
Human CTLA-4
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a fully-humanized IgG2 monoclonal antibody that binds to human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on the activated T cells. Binding to CTLA-4 results in inhibition of its association with the ligands B7-1 (CD80) and B7-2 (CD86), thereby preventing the downregulation of T-cell activation and inhibition of tumor growth. The original drug is currently undergoing clinical trials for the treatment of several cancers such as melanoma, mesothelioma and non-small cell lung cancer
Storage Temperature:
-80°C