Anti-PD-1 (Toripalimab), Humanized Antibody
Catalogue number:
A2161-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
Shipping is calculated in checkout
This product is no longer available to order.
Antibody Host:
Recombinant
Species Reactivity:
Human
Antibody Isotype:
IgG4, kappa
Antibody Type:
Monoclonal
Immunogen:
Human PD-1
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a humanized IgG4 recombinant monoclonal antibody that binds to programmed death receptor-1 (PD-1) and prevents the interaction with its ligands PD-L1 and PD-L2. This results in the activation of T-cell mediated immune response and inhibits tumor cell growth. The original drug received approval in China in 2018 as the second line of treatment for melanoma. Currently, the drug is evaluated for efficacy and toxicity in Phase I-III clinical trials for nasopharyngeal carcinoma, head and neck squamous cell carcinoma and gastric adenocarcinoma
Storage Temperature:
-80°C