Anti-IL5 (Mepolizumab), Humanized Antibody
Catalogue number:
A2158-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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This product is no longer available to order.
Antibody Host:
Recombinant
Species Reactivity:
Human
Antibody Isotype:
IgG1, kappa
Antibody Type:
Monoclonal
Immunogen:
Human IL-5
- Data sheet: View or download
Product Description:
The research-grade biosimilar is a humanized IgG1 kappa monoclonal antibody that acts as an antagonist for IL-5. IL-5 is a major cytokine that plays an important role in the recruitment, activation, growth, differentiation, and survival of eosinophil cells. The antibody binds to IL-5 and inhibits its interaction with the IL-5 receptor, localized on the surface of eosinophil cells. This prevents IL-5 mediated signaling and results in reduced survival of eosinophil cells and reduced inflammation. The original drug received approval from the FDA in 2015 for the treatment of severe eosinophilic asthma.
Storage Temperature:
-80°C