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Anti-IL5 (Mepolizumab), Humanized Antibody

Supplier:
Catalogue number:
A2158-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£581.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

The research-grade biosimilar is a humanised IgG1 kappa monoclonal antibody that acts as an antagonist for IL-5. IL-5 is a major cytokine that plays an important role in the recruitment, activation, growth, differentiation, and survival of eosinophil cells. The antibody binds to IL-5 and inhibits its interaction with the IL-5 receptor, localised on the surface of eosinophil cells. This prevents IL-5 mediated signaling and results in reduced survival of eosinophil cells and reduced inflammation. The original drug received approval from the FDA in 2015 for the treatment of severe eosinophilic asthma.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-80°C

Antibody Host:

Recombinant

Antibody Isotype:

IgG1, kappa

Formulation:

In PBS, pH 7.5

Antibody Type:

Monoclonal

UNSPSC Code:

12352203

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