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Anti-IL-23α (Guselkumab), Human IgG1 Antibody

Supplier:
Catalogue number:
A2147-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£581.00 Estimated delivery Wed 30 Jun
Shipping is calculated in checkout

Guselkumab is a fully human IgG1 lambda monoclonal antibody that is produced in Chinese Hamster Ovary (CHO) cells. This monoclonal antibody selectively inhibits IL-23 by binding to the p19 subunit of IL-23, blocking its interaction with the receptor (IL-23R), and inhibiting the release of proinflammatory chemokines and cytokines. The antibody was developed by Janssen Biotech and received FDA approval for the treatment of moderate to severe plaque psoriasis. Guselkumab is marketed under the trade name TREMFYA®

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-80°C

Antibody Host:

Human

Antibody Isotype:

IgG1, lambda

Formulation:

In PBS, pH 7.5

Antibody Type:

Monoclonal

UNSPSC Code:

12352203

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