Anti-IL-23α (Guselkumab), Human IgG1 Antibody
Catalogue number:
A2147-100
Supplier:
BioVision
Size:
100 µg _$$_
Product is available in:
N/A
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Antibody Host:
Human
Species Reactivity:
Human
Antibody Isotype:
IgG1, lambda
Antibody Type:
Monoclonal
Immunogen:
Guselkumab
- Data sheet: View or download
Product Description:
Guselkumab is a fully human IgG1 lambda monoclonal antibody that is produced in Chinese Hamster Ovary (CHO) cells. This monoclonal antibody selectively inhibits IL-23 by binding to the p19 subunit of IL-23, blocking its interaction with the receptor (IL-23R), and inhibiting the release of proinflammatory chemokines and cytokines. The antibody was developed by Janssen Biotech and received FDA approval for the treatment of moderate to severe plaque psoriasis. Guselkumab is marketed under the trade name TREMFYA®
Storage Temperature:
-80°C