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Anti-USP2 Antibody

Supplier:
Catalogue number:
A2146-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£428.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease that is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX, and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

  • Data sheet/protocol: View or download
  • Applications: Immunofluorescence (IF),Western Blotting
Product Type:

Antibodies

Species Reactivity:

Mouse,Human

Storage Temp:

-20°C

Antibody Host:

Rabbit

Antibody Isotype:

IgG

Formulation:

In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300

Antibody Type:

Polyclonal

UNSPSC Code:

12352203

Anti-USP2 Antibody

Anti-USP2 Antibody

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