www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Anti-IL-1β (Canakinumab), Human IgG1 Antibody

Supplier:
Catalogue number:
A2144-100
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£530.00 Estimated delivery Wed 23 Jun
Shipping is calculated in checkout

Canakinumab is a recombinant human IgG1 kappa monoclonal antibody that is produced in murine Sp2/0-Ag14 cell line. This antibody binds to and neutralises human IL-1β preventing association with its receptor and subsequent inflammatory signaling cascade. The antibody neither has cross-reactivity with IL-1α nor with the Interleukin 1 receptor, type I (IL1R1). Canakinumab was developed by Novartis to treat rheumatoid arthritis. It received FDA approval in 2009 to treat cryopyrin-associated periodic syndromes (CAPS). Additionally, in 2016, Canakinumab received approval for the treatment of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS), Hyperimmunoglobulinemia D Syndrome (HIDS)/Mevalonate Kinase Deficiency (MKD) and Familial Mediterranean Fever (FMF). This antibody is marketed under the trade name Ilaris®.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-80°C

Antibody Host:

Recombinant

Antibody Isotype:

IgG1, kappa

Formulation:

In PBS pH 7.5

Antibody Type:

Monoclonal

UNSPSC Code:

12352203

Details Cat number & supplier Size Price
Anti-IL-6 (Siltuximab), Chimeric Antibody A2143-100 · BioVision
A2143-100
BioVision
100 µg £581.00
100 µg
view
Anti-IgE (Omalizumab), Humanized Antibody A2145-100 · BioVision
A2145-100
BioVision
100 µg £530.00
100 µg
view
Anti-TNF-α (Certolizumab Pegol), Humanized Antibody A2142-100 · BioVision
A2142-100
BioVision
100 µg £581.00
100 µg
view
Anti-USP2 Antibody A2146-100 · BioVision
A2146-100
BioVision
100 µg £428.00
100 µg
view
Anti-TNF-α (Golimumab), Human IgG1 Antibody A2141-100 · BioVision
A2141-100
BioVision
100 µg £581.00
100 µg
view
Anti-IL-23α (Guselkumab), Human IgG1 Antibody A2147-100 · BioVision
A2147-100
BioVision
100 µg £581.00
100 µg
view
Anti-α4β7 Integrin (Vedolizumab), Humanized Antibody A2140-100 · BioVision
A2140-100
BioVision
100 µg £581.00
100 µg
view